WHI strives to improve health through research on risk factors, prevention, and early detection of serious health conditions, so postmenopausal women thrive.

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Impacting lives through groundbreaking research

Impacting lives through groundbreaking research
161,000 +study participants
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5.3 millionspecimen vials collected and documented
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12,600fewer cases of breast cancer each year as a result of WHI research
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The Women’s Health Initiative is a landmark study that has had a huge impact on medical practice and public health.

— Gary H. Gibbons, M.D., NHLBI Director
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2,274papers published to date using WHI datapapers published using WHI data
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WHI News

2023 WHI Investigators Meeting

2023 WHI Investigators Meeting

Registration is now open for the 2023 WHI Investigators Meeting! Please see the attached link for registration information. More details to follow.
WHI Response to NYT article "Women have been misled about menopause"

WHI Response to NYT article "Women have been misled about menopause"

On February 1st, the NYT Magazine published an article describing some perimenopausal women’s struggles with menopause and the role of hormone therapy in relieving symptoms. The WHI hormone trials are cast in a rather unfavorable light in this article, mostly because the trial was not designed to address the concerns of perimenopausal women. The WHI Steering Committee has written a letter to the editor of the NYT in response, which can be found below.
Remembering Dr. Lewis Kuller - MEMORIAL INFO AVAILABLE

Remembering Dr. Lewis Kuller - MEMORIAL INFO AVAILABLE

What a difficult year this has been for us. Sadly, we must inform you of the passing of one of the major intellectual leaders in the WHI. Dr. Lewis Kuller passed away last night after some months of declining health.
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Recent Publications

Association of social support with mild cognitive impairment and dementia among older women: Women’s Health Initiative Memory Study

Alexander Posis et al., 2023/undefined PubMed #36565123

Long-term exposure to ambient particulate matter and stroke etiology: Results from the Women’s Health Initiative

Erin Kulick et al., 2023/5 PubMed #36813070

Diabetes, metformin use and risk of non-Hodgkin's lymphoma in postmenopausal women: A prospective cohort analysis in the Women's Health Initiative

Zikun Wang et al., 2023/4 PubMed #36444502

Association of Preterm Birth With Prevalent and Incident Hypertension, Early-Onset Hypertension, and Cardiovascular Disease in the Women's Health Initiative

Pamela Brewer et al., 2023/4 PubMed #36791524

Supplemental B-vitamins and risk of upper gastrointestinal cancers in the Women’s Health Initiative

Theodore Brasky et al., 2023/3 PubMed #36895169

Artificially sweetened beverages and urinary incontinence - A secondary analysis of the Women’s Health Initiative Observational Study (WHI-OS)

Nancy Ringel et al., 2023/3 PubMed #36515559

Short-term Air Pollution Levels and Blood Pressure in Older Women

Jeff Yanosky et al., 2023/3 PubMed #36722810

Resiliency among Women’s Health Initiative women aged 80 and older by race, ethnicity, and neighborhood socioeconomic status

Jessica Krok-Schoen et al., 2023/3 PubMed #36933001

Cardiovascular Disease and Mortality in Black Women Carrying the Amyloidogenic V122I Transthyretin Gene Variant

Bernhard Haring et al., 2023/3 PubMed #36930136

Total energy expenditure as assessed by doubly labeled water and all-cause mortality in a cohort of postmenopausal women

Ross Prentice et al., 2023/3 PubMed #36889672

Accelerometer-measured physical activity and postmenopausal breast cancer incidence in the Women's Health Accelerometry Collaboration

Humberto Parada Jr. et al., 2023/2 PubMed #36812131

Plasma proteins related to inflammatory diet predict future cognitive impairment

Michael Duggan et al., 2023/2 PubMed #36737481

Longitudinal patterns of abdominal visceral and subcutaneous adipose tissue, total body composition, and anthropometric measures in postmenopausal women: Results from the Women's Health Initiative

Hailey Banack et al., 2023/2 PubMed #36739471

Frequency of Consuming Breakfast Meals and After-Dinner Snacks Is not Associated with Postmenopausal Breast Cancer Risk: Women's Health Initiative Observational Study

Valeria Elahy et al., 2023/2 PubMed #36828152

Pregnancy loss and risk of incident CVD within 5 years: Findings from the Women's Health Initiative

Catherine Wright et al., 2023/2 PubMed #36895838

Air pollution and decreased bone mineral density among Women's Health Initiative participants

Diddier Prada et al., 2023/2 PubMed #36820096

Evaluation of the association between circulating IL-1β and related cytokines and incident atrial fibrillation in a cohort of postmenopausal women

Marco Perez et al., 2023/1 PubMed #36646198

An Association Between Large Optic Cupping and Total and Regional Brain Volume: The Women's Health Initiative

Thasarat S. Vajaranant et al., 2023/1 PubMed #36638905

Accelerometer-measured physical activity and sitting with incident mild cognitive impairment or probable dementia among older women

Steve Nguyen et al., 2023/1 PubMed #36695426

Dietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women's Health Initiative

Monica Daniela Zuercher et al., 2023/1 PubMed #36631866

Long-term Trajectories of Physical Function Decline in Women With and Without Cancer

Elizabeth Cespedes Feliciano et al., 2023/1 PubMed #36656572

An integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling

Tamar Sofer et al., 2023/1 PubMed #36721044

Epigenome-wide meta-analysis of BMI in nine population-based cohorts: examining the utility of epigenetically predicted BMI

Whitney Leet et al., 2023/1 PubMed #36649705

Alcohol and Smoking Cessation as Potential Modulators for Smoking-Associated Psoriasis Risk in Postmenopausal Women: The Women's Health Initiative

Alfred A. Chan et al., 2023/1 PubMed #36662365

Association between urinary phthalate biomarker concentrations and adiposity among postmenopausal women

Katherine Reeves et al., 2023/1 PubMed #36706896

Association of calcium and vitamin D supplementation with cancer incidence and cause-specific mortality in Black women: Extended follow-up of the Women's Health Initiative calcium-vitamin D trial

Ikuko Kato et al., 2023/1 PubMed #36650676

Association of Artificially Sweetened Beverage Consumption and Urinary Tract Cancers in the Women's Health Initiative Observational Study

Nancy Ringel et al., 2022/12 PubMed #36601047

Chocolate consumption in relation to all-cause and cause-specific mortality in women: The Women’s Health Initiative

Yangbo Sun et al., 2022/12 PubMed #36549566

Long-term aircraft noise exposure and risk of hypertension in postmenopausal women

Daniel D. Nguyen et al., 2022/12 PubMed #36502895

Association between dietary inflammatory potential and mortality after cancer diagnosis in the Women's Health Initiative

Susan Steck et al., 2022/12 PubMed #36482189

Want to view more works by WHI investigators? Visit our publications page