WHI strives to improve health through research on risk factors, prevention, and early detection of serious health conditions, so postmenopausal women thrive.

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Impacting lives through groundbreaking research

Impacting lives through groundbreaking research
161,000 +study participants
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5.3 millionspecimen vials collected and documented
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12,600fewer cases of breast cancer each year as a result of WHI research
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The Women’s Health Initiative is a landmark study that has had a huge impact on medical practice and public health.

— Gary H. Gibbons, M.D., NHLBI Director
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1,800papers published to date using WHI datapapers published using WHI data
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WHI News

Remembering Dr. Lewis Kuller

Remembering Dr. Lewis Kuller

What a difficult year this has been for us. Sadly, we must inform you of the passing of one of the major intellectual leaders in the WHI. Dr. Lewis Kuller passed away last night after some months of declining health.
Remembering Dr. Rebecca Jackson

Remembering Dr. Rebecca Jackson

It is with a heavy heart that we share the news of the passing yesterday morning of our most valued colleague and friend, Dr. Rebecca Jackson.
Dr. JoAnn Manson, Champion of Women’s Health, to Receive Alma Dea Morani Renaissance Woman Award

Dr. JoAnn Manson, Champion of Women’s Health, to Receive Alma Dea Morani Renaissance Woman Award

JoAnn E. Manson, MD, DrPH, MACP, whose pioneering research has contributed to the understanding of the causes of chronic diseases, including cardiovascular disease, diabetes, and cancer, is the 2022 recipient of the Alma Dea Morani Renaissance Woman Award, the highest honor bestowed by the Women in Medicine Legacy Foundation.
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Recent Publications

Dietary patterns and urinary phthalate exposure among postmenopausal women of the Women’s Health Initiative

Gabriela Vieyra et al., 2022/11 PubMed #36356671

The relationship between depressive symptoms and subtypes of mild cognitive impairment in post-menopausal women: Results from the Women's Health Initiative Memory Study

Laura Korthauer et al., 2022/11 PubMed #36205005

Effect of low-fat dietary modification on incident open-angle glaucoma

Thasarat S. Vajaranant et al., 2022/11 PubMed #36410561

Long-term air pollution and risk of amyotrophic lateral sclerosis mortality in the Women’s Health Initiative Cohort

Evelyn Talbott et al., 2022/10 PubMed #36220441

Adherence to the American Cancer Society Guidelines on nutrition and physical activity for cancer prevention and obesity-related cancer risk and mortality in Black and Latina Women's Health Initiative participants

Margaret Pichardo et al., 2022/10 PubMed #35996861

Association between cognitive function and large cup-disc-ratio, accounting for cup-disc-ratio genetic risk score

Thasarat S. Vajaranant et al., 2022/10 PubMed #36315511

The severity of individual menopausal symptoms, cardiovascular disease, and all-cause mortality in the Women’s Health Initiative Observational Cohort

Matthew Nudy et al., 2022/10 PubMed #36219813

Women’s Health Initiative Clinical Trials: The effect of menopausal hormone therapy on blood pressure in postmenopausal women with hypertension

Xuezhi Jiang et al., 2022/10 PubMed #36256926

Heart rate variability and the risk of heart failure and its subtypes in post-menopausal women: The Women's Health Initiative study

Muhammad Baig et al., 2022/10 PubMed #36282885

Long term pelvic fracture and all-cause mortality risk after pelvic cancer and pelvic radiation: Findings from the Women’s Health Initiative (WHI)

Rebecca Nelson et al., 2022/10 PubMed #36305666

Added Sugar, Sugar-Sweetened Beverages, and Artificially Sweetened Beverages and Risk of Cardiovascular Disease: Findings from the Women's Health Initiative and a Network Meta-Analysis of Prospective Studies

Kenneth Lo et al., 2022/10 PubMed #36296910

Racial differences in anthropometric measures as risk factors for triple-negative breast cancer

Fengge Wang et al., 2022/9 PubMed #36129619

Continuity of care among postmenopausal women with cardiometabolic diseases in the United States early during the COVID-19 pandemic: Findings from the Women's Health Initiative

Eugenia Wong et al., 2022/9 PubMed #36087113

Sleep duration, plasma metabolites, and obesity and diabetes: A metabolome-wide association study in US women

Celine Vetter et al., 2022/9 PubMed #36130143

Association of sleep duration and insomnia with metabolic syndrome and its components in the Women's Health Initiative

Rita Peila et al., 2022/9 PubMed #36104689

The association of epigenetic age acceleration and multimorbidity at age 90 in the Women’s Health Initiative

Purva Jain et al., 2022/9 PubMed #36107798

Constitutional BRCA1 methylation and risk of incident triple-negative breast cancer and high-grade serous ovarian cancer

Per Eystein Lonning et al., 2022/9 PubMed #36074460

Estrogen therapy and breast cancer in randomized clinical trials: a narrative review

Kathy Pan et al., 2022/9 PubMed #35969882

Blood pressure variability and heart failure hospitalization: Results from the Women's Health Initiative

Bernhard Haring et al., 2022/9 PubMed #35525685

Low diastolic blood pressure and mortality in older women. Results from The Women’s Health Initiative Long Life Study

Sylvia Wassertheil-Smoller et al., 2022/9 PubMed #35522983

Differences in metabolomic profiles between Black and White women and risk of coronary heart disease: an observational study of women from four US cohorts

Jie Hu et al., 2022/9 PubMed #36052690

Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of U.S. adults

Katie Holliday et al., 2022/9 PubMed #35500859

Chronic oxidative stress as a marker of long-term radiation-induced cardiovascular outcomes in breast cancer

Alexi Vasbinder et al., 2022/9 PubMed #36178659

The portfolio diet and incident type 2 diabetes: Findings from the Women's Health Initiative prospective cohort study

Andrea Glenn et al., 2022/9 PubMed #36162007

Dietary selenium intake and thyroid cancer risk in postmenopausal women

Xiaojingyuan Xu et al., 2022/9 PubMed #36174395

Relationship between BMI trajectories and cardiometabolic outcomes in postmenopausal women: a growth mixture modeling approach

Hailey Banack et al., 2022/8 PubMed #35469929

Healthy lifestyle index and the risk of ductal carcinoma in situ of the breast in the Women’s Health Initiative

Rita Peila et al., 2022/8 PubMed #35429338

Dietary protein sources, mediating biomarkers, and incidence of type 2 diabetes: Findings From the Women's Health Initiative and the UK Biobank

Jie Li et al., 2022/8 PubMed #35713602

Broad clinical manifestations of polygenic risk for coronary artery disease in the Women’s Health Initiative

Shoa Clark et al., 2022/8 PubMed #36034645

Intention-to-Treat Comparisons in Randomized Trials

Ross Prentice et al., 2022/8 PubMed #99999999

Want to view more works by WHI investigators? Visit our publications page.